2010 Softball Schedule
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 35-21 | .625 | 15-13 | .536 | Lost 2 | 19-4 | 14-13 | 2-4 |
| Date | Opponent | Notes | Result | Time/Status | Links |
| Feb. 11 | vs. Stanford | L, 10-2 | Final | Box Score | |
| Feb. 12 | vs. McNeese State | W, 2-1 | Final | Box Score | |
| at Hawaii | L, 9-0 | Final | Box Score | ||
| Feb. 13 | vs. Stanford | L, 5-2 | Final | Box Score | |
| vs. McNeese State | W, 10-2 | Final | Box Score | ||
| Feb. 18 | Centenary College | W, 11-1 | Final | Box Score | |
| Boston College | W, 6-5 | Final | Box Score | ||
| Feb. 20 | Boston College | W, 3-1 | Final | Box Score | |
| Southern | W, 11-0 | Final | Box Score | ||
| Feb. 21 | Southern | W, 14-2 | Final | Box Score | |
| Feb. 25 | Houston Baptist | W, 6-2 | Final | Box Score | |
| Feb. 26 | North Dakota | W, 11-5 | Final | Box Score | |
| UL Monroe | W, 7-6 | Final | Box Score | ||
| Feb. 27 | North Dakota | W, 9-3 | Final | Box Score | |
| Feb. 28 | UL Monroe | W, 4-2 | Final | Box Score | |
| Mar. 2 | at UTSA * | L, 12-2 | Final | Box Score | |
| at UTSA * | W, 6-3 | Final | Box Score | ||
| Mar. 3 | at UTSA * | L, 5-4 | Final | Box Score | |
| Mar. 6 | at Central Arkansas * | W, 2-1 | Final | Box Score | |
| at Central Arkansas * | W, 13-5 | Final | Box Score | ||
| Mar. 7 | at Central Arkansas * | L, 7-2 | Final | Box Score | |
| Mar. 9 | at Texas A&M | W, 4-3 | Final | Box Score | |
| at Texas A&M | L, 8-0 | Final | Box Score | ||
| Mar. 13 | Nicholls * | W, 3-0 | Final | Box Score | |
| Nicholls * | W, 6-0 | Final | Box Score | ||
| Mar. 20 | at Texas State * | L, 4-3 | Final | Box Score | |
| Mar. 21 | at Texas State * | L, 7-6 | Final | Box Score | |
| at Texas State * | W, 11-7 | Final | Box Score | ||
| Mar. 25 | at Texas | L, 13-4 | Final | Box Score | |
| at Texas | W, 8-4 | Final | Box Score | ||
| Mar. 27 | Northwestern State * | W, 4-0 | Final | Box Score | |
| Northwestern State * | W, 4-3 | Final | Box Score | ||
| Mar. 28 | Northwestern State * | W, 3-0 | Final | Box Score | |
| Apr. 2 | at Stephen F. Austin * | L, 10-3 | Final | Box Score | |
| at Stephen F. Austin * | L, 10-2 | Final | Box Score | ||
| Apr. 3 | at Stephen F. Austin * | L, 4-3 | Final | Box Score | |
| Apr. 7 | Prairie View | W, 4-0 | Final | Box Score | |
| Prairie View | W, 17-0 | Final | Box Score | ||
| Apr. 10 | Sam Houston State * | L, 4-2 | Final | Box Score | |
| Sam Houston State * | L, 9-8 | Final | Box Score | ||
| Apr. 11 | Sam Houston State * | L, 5-0 | Final | Box Score | |
| Apr. 13 | at Prairie View | W, 12-2 | Final | Box Score | |
| at Prairie View | W, 16-8 | Final | Box Score | ||
| Apr. 17 | at McNeese State * | L, 5-4 | Final | Box Score | |
| at McNeese State * | W, 11-2 | Final | Box Score | ||
| Apr. 18 | at McNeese State * | W, 2-1 | Final | Box Score | |
| Apr. 24 | at Houston Baptist | W, 6-0 | Final | Box Score | |
| at Houston Baptist | L, 8-0 | Final | Box Score | ||
| May. 1 | UT Arlington * | L, 5-3 | Final | Box Score | |
| UT Arlington * | W, 6-4 | Final | Box Score | ||
| May. 2 | UT Arlington * | W, 4-3 | Final | Box Score | |
| May. 8 | at Southeastern Louisiana * | W, 4-3 | Final | Box Score | |
| at Southeastern Louisiana * | W, 13-5 | Final | Box Score | ||
| May. 9 | at Southeastern Louisiana | W, 8-7 | Final | Box Score | |
| May. 13 | vs. McNeese State | L, 6-0 | Final | Box Score | |
| May. 14 | vs. UT Arlington | L, 3-2 | Final | Box Score | |
| Home games in bold. *Conference Game All Times Central Standard Time | |||||
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